WEIGHT LOSS · GUIDES

Changing or lowering your dose.

The right dose is the lowest one that works for you — not the highest you can take. Here's what a step-down feels like, and the signals worth telling us about.

Last updated July 2026 · Written by Habibah Hafeji · Clinically reviewed by Wasim Bharuchi What to report ↓
Changing or lowering your dose.
The lowest effective dose

The lowest effective dose

More isn't better — the aim is the smallest dose that keeps your appetite settled and the results steady, with the fewest side effects. Sometimes that means going down, and that's a good outcome, not a setback.

What to expect

01

Appetite may return a little

A small rise in hunger is common and often settles.

02

Side effects usually ease

Lower doses are typically gentler on your stomach.

03

Weight may plateau

Holding steady at a lower dose is a normal, fine outcome.

04

Give it a few weeks

Judge the change over weeks, not days.

What's worth reporting

What's worth reporting

Tell us if hunger comes back strongly, if weight climbs steadily again, or if side effects are still troubling you at the lower dose. These help your prescriber get the level right.

Dose changes are always set by your prescriber.

Never adjust it yourself. Message the pharmacy team on live chat at yourmedicals.co.uk or call 0116 507 0486 and we'll review it with you.

Fair questions

Will I regain weight on a lower dose?

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Can I go back up if I need to?

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Is a plateau a sign to change dose?

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How do I request a change?

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